Different Course of Narcolepsy Diagnosed by Multiple Sleep Latency Test: A Single Center Experience

Background and Objective Several studies have raised questions about determining the diagnosis of narcolepsy using multiple sleep latency test (MSLT). In this study, we investigated diagnostic change in type 1 (NT1) 2 (NT2) MSLT with long-term interval.Methods retrospective demographic characteristics, polysomnography (PSG), parameters were compared at baseline between NT1 NT patients. Then, re-tests conducted a mean follow-up 8.48 years patients 7.05 2.Results Seventy-four (58 16 NT2) study. At baseline, data showed larger body mass index value, more paralysis, hypnogogic hallucination to 2. Also, MSLT, shorter higher number onset rapid eye movement periods (SOREMPs) observed than those On 6.9% (n = 4) 50% 8) NT2 did not satisfy previous diagnosis. Furthermore, all groups who had repeated-MSLT, less SOREMPs be accompanied by negative MSL follow-up.Conclusions The result was stable Therefore, it is recommended repeat regular intervals do prospective multi-site survey for accurate confirmation central hypersomnia.